Flux balance analysis predicts Warburg-like effects of mouse hepatocyte deficient in miR-122a.
The liver is a vital organ involving in various major metabolic functions in human body.MicroRNA-122 (miR-122) plays an important role in the regulation of liver metabolism, but its intrinsic physiological functions require further clarification.This study integrated the genome-scale metabolic model of hepatocytes and mouse experimental data with g